Abstract
LIPID PROFILE AND C-REACTIVE PROTEIN IN SUDANES WOMEN USING CONTRACEPTIVE IN KHARTOUM STATE

Aisha Ahmed Abedalkhalig Mohamed, Amna O. M. Elzein and Nassr Eldin M. A. Shrif*

ABSTRACT

Background: Continual use of contraceptives have been linked to risk of cardiovascular disease. Objectives: This study was aimed to assess serum levels of lipid profile and C - reactive protein as indicator of cardiovascular disease in women using contraceptive. Material and Methods: In central health care based matched cross sectional study was conducted in Khartoum state –Sudan during the period from January 2015 to march 2016. After signing written informed consent, blood sample was collected from 100 fasting women using contraceptive as case group and 70 fasting women not using contraceptive as control group aged from (25-40)years and serum level of cholesterol, triglyceride, HDL, LDL and CRP was measured using spectrophotometrical methods. Data were collected using structural questionnaire. Data analysis was carried out by means of statistical package for social science (SPSS). Result: The study compared between women using contraceptives and non using contraceptives and showed significant increase in mean of serum level of total cholesterol(194.2±55.3vs170±29.3), triglyceride (188±87vs129.4±33.1), LDL(130±50 vs 93±31.3) and CRP(7.3±5.8 vs 4.7±3.0) (p< value 0.05) and decreased in HDL (24.4±11.3 vs 51.2±14.5), (p value <0.05). Age and body mass index did not show significant difference when compared with control group. Conclusion: continual use of contraceptive is associated with increased level of cholesterol, triglyceride, LDL and CRP and decrease in HDL and this may be linked to increase risk of cardiovascular disease.

Keywords: Lipid profile, Contraceptive, Sudan.


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