Abstract
ASSOCIATION BETWEEN PSORIASIS DISEASE AND METABOLIC SYNDROME

Nusiba Musa*, Ekram Hamza and Tarig Mohmed

ABSTRACT

Background: Psoriasis is a disorder characterized by a chronic inflammation of skin, which recently has been demonstrated that was associated with high risk of cardiovascular diseases. Metabolic syndrome is a significant predictor of these events. Methodology: A hospital-based case control study performed on 105 candidates (35 patients with plaque type psoriasis, 35 apparently healthy person, and 35 patients with non psoriatic skin diseases) all matched for age and gender. Results: Metabolic syndrome was significantly increased in patients with psoriasis (p-value 0.028). The proportions of diabetes, hypertension, dyslipidemia, and waist circumference were insignificantly elevated in psoriatic compared with healthy and non psoriatic skin diseases people (p-value 0.171, 0.172, 0.704, 0.267 and 0.672 respectively). Conclusion: The metabolic syndrome was a higher among individual with psoriasis, and strongly correlated with obesity, so patient should be advised to change their life style, and early screening and monitoring of metabolic syndrome and its components may be an important issue to reduce this negative consequences of psoriasis.

Keywords: Psoriasis, metabolic syndrome, cardiovascular disease, comorbidity.


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