Abstract
STANDARDIZATION AND PHYTOCHEMICAL SCREENING OF MUCUNA PRURIENS

Rakam Gopi Krishna and Raja Sundararajan.*

ABSTRACT

Mucuna pruriens belongs to the family Fabaceae and it is commonly known as Velvet bean. Mucuna pruriens is the most popular drug in Ayurvedic system of medicine. Various parts of Mucuna pruriens are generally used for the treatment of impotence, diabetes mellitus, bone fractures, cough, dog bite, cancer and madness. The present study was designed for the standardization and phytochemical screening of various extracts of whole plant powder of Mucuna pruriens. Physicochemical parameters like loss on drying, determination of total ash, determination of pH range and acid insoluble ash of whole plant powder of Mucuna pruriens were estimated based on the methods recommended by World Health Organization. Standardization includes the estimation of physicochemical parameters such as loss on drying, determination of pH range, determination of total ash, determination of water soluble ash, determination of acid insoluble ash, determination of sulfated ash and determination of hot water & ethanol-extractable matter. Preliminary phytochemical screening and TLC studies for all the extracts like chloroform, ethyl acetate and methanol were carried out by standard methods. The result of physicochemical parameters values was found to be within the ranges and valuable to estimate the chemical constituents present in the crude drug. Report of phytochemical screening for all the extracts revealed the presence of various phytoconstituents like alkaloids, flavonoids, tannins and phenolic compounds in the leaves of Mucuna pruriens The generated information of the present study will provide data which is helpful in the correct identification & authentication of this medicinal plant and may help in preventing its adulteration.

Keywords: Mucuna Pruriens, Standardization, Phytoconstituents, Adulteration.


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