Abstract
AN OBSERVATIONAL STUDY ON THE EFFECT OF THYROID DISORDERS ON VARIOUS ORGAN SYSTEMS

D.Geetha Rani, R.Deepthi*, Dr.P.Kishore, Dr.B.Sridhar

ABSTRACT

Thyroid diseases are the most common endocrine disorders world-wide. India is no exception. India is in the transition phase from iodine deficiency to iodine sufficiency, and this is expected to change the thyroid status of the population. Thyroid disorders for the most part are controllable. However, uncontrolled thyroid diseases can produce serious effects on other parts of the body. The present study was aimed to elucidate the effect of thyroid disorders on various organ systems of the body. It is an symptom based observational study performed for 6months period in randomly selected 204 subjects among whom, the majority of the patients were suffering with hypothyroidism (77.9%) compared to hyperthyroidism (22.05%). Majorly effected organ system is reproductive system (39.09%) followed by Digestive system (21.3%), CNS (13.18%), Haemopoietic system (10.9%), Hepatic system (6.81%), CVS (6.36%), Skeletal system(2.27%). Effect of thyroid disorders on reproductive system (P=0.0109**), central nervous system (P=0.0005**), cardiovascular system (P=0.0001**), hepatic system (P=0.0426**) was found to be statistically significant. Diagnosing the thyroid disorders in early stages can minimize their deletorious effects on various organ systems of the body. Therefore it is very important for a clinical pharmacist to educate the patient regarding the importance of symptoms awareness and medication adherence to the prescribed regimen in thyroid disorders which will go a long way in preventing reproductive, cardiovascular and central nervous system complications in future.

Keywords: Thyroid disorders, Thyroid effect, CVS, CNS, Medication adherence.


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