Abstract
A COMPARATIVE STUDY ON ANTI DIABETIC ACTIVITY OF CRUDE EXTRACTS OF ENDOPHYTIC FUNGI FROM SEA WEED GRACILARIA CORTICATA

R. Anusha* and R. Ushasri*

ABSTRACT

Diabetes, often referred to by doctors as Diabetes mellitus, describes a group of metabolic diseases in which the person has high blood glucose (blood sugar).Insulin is a hormone that is produced by the pancreas.. Inhibition of α-amylase, enzyme that plays a role in digestion of starch and glycogen, is considered a strategy for the treatment of disorders in carbohydrate uptake, such as diabetes. Gracilaria corticata have been used since ancient times as food, fodder, and fertiliser and as source of médicine. Gracilaria corticata. Endophytic fungi are one of the potential natural resources for new ant diabetic compound sources. The aim of the study was to compare anti diabetic activity of crude extracts of Endophytic fungi from Gracilaria corticata against diabetes. Endophytic fungi were isolated from seaweed Gracilaria coricata, characterized and identified based on morphological and biochemical characters. The identified endophytic fungi were tested for invitro antidiabetic activity by alpha amylase inhibition assay, method the higehest percentage of alpha amylase inhibition at the concentration of 500μl of ethanolic extract of A. niger that showed 41.4% followed by penicillium (39%) A.fumigatus (33.4%) Phoma spp (28.9%) and Syncephalastrum racemosum (23.7%) in comparison with acetone crude extracts of Penicillium (25.2%), Phoma spp (24.2%), A.fumigatus (21.3%), Syncephalastrum racemosum (19.4%), A.niger (17.4%).

Keywords: Endo phytic fungi, DNS, Gracilaria corticata, Diabetes, Alpha amylase.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • EJBPS NEW ISSUE PUBLISHED

    Its Our pleasure to inform you that, EJBPS December 2017 Issue has been Published, Kindly check it on http://www.ejbps.com/ejbps/current_issues

  • DECEMBER ISSUE PUBLISHED

    DECEMBER 2017 Issue has been successfully launched on 1 December 2017

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 3.881 to 4.382 due to high quality Publication at International Level.

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT