Abstract
UNUSUAL FATTY ACIDS INCORPORATED INTO NATURAL PEPTIDES DERIVED FROM SEAWEEDS AND INVERTEBRATES

*Valery M. Dembitsky

ABSTRACT

This review is a first comprehensive survey focuses on the unique, unusual and rare fatty acids incorporated into natural peptides derived from seaweeds and invertebrates. Fatty acids incorporated into lipopeptides are of particular interest because many of them display important biological activities and possess antibacterial, antimicrobial, antifungal, antitumour, phototoxic, HIV-inhibitory, or immunosuppressive properties. There is no doubt that they are of great interest, especially for the medical chemistry and pharmaceutical industries. This review presents structures and describes cytotoxic activities of more than 100 unusual fatty acids incorporated into natural lipopeptides isolated from seaweeds and invertebrates.

Keywords: Fatty acids, lipopeptides, peptides, seaweeds, sponges, mollusks, tunicate.


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