Abstract
SIMPLE SPECTROPHOTOMETRIC ASSAY AND BIOLOGIACL EVALUATION OF ZALCITABINE

V. L. Janardhana Reddy*, P. Raveendra Reddy and P. Ravisankara Reddy

ABSTRACT

A Simple, precise, accurate and economical spectrophotometric method was developed and validated for simultaneous estimation of zalcitabine was quantified using their absorptivity values at selected wavelengths, viz., 268nm and 263nm respectively. The accuracy and reproducibility of the proposed method was statistically validated by recovery studies. The simultaneous equation method permits simple, rapid and direct determination of zalcitabine commercially available combined dosage form without previous separations and can therefore be used for routine analysis.

Keywords: Zalcitabine, Simultaneous equation Method.


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