Abstract
FORMULATION AND EVALUATION OF BILAYER TABLETS OF TENOFOVIR DISOPROXIL FUMARATE AND LAMIVUDINE

P. Rama Krishna Reddy*, Dr. Pankaj Kumar Sharma, Dr. Jaya Sharma and B. Chandana

ABSTRACT

The present study was carried out for developing the formulation of Bilayer tablets of Tenofovir, Lamivudine. SR16 contain HPMC K100M (Hydrophyllic Polymer) and Ethyl Cellulose (Hydrophobic Polymer). Formulations containing Eudragit S100 and Eudragit L100 not retard the drug release 24 hours hence those formulations did not take into consideration. SR16 formulation was shown best drug release (97.86%) within 24 hours. Finally Concluded that SR16 formulation was optimised formulation. SR16 which follows zero order release kinetics.

Keywords: Lamivudine, Bilayer tablets.


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