S. Senthil Kumar*, R. Rekka, Jils Thankachan and Treesa Santhosh


The present study was aimed to evaluate the aphrodisiac potential and reproductive safety profile of methanolic extract of Ficus auriculata fruit in male Wistar albino rats. The dried fruit powder of Ficus auriculata was subjected to methanolic extraction adopting Soxhlet method. Male wistar albino rats weighing between 170 and 220 gm were used for this study. The aphrodisiac and reproductive toxicity potential were evaluated after grouping the rats into 3, namely control and methanolic fruit extract of Ficus auriculata treated groups at two dose levels, 250 and 500 mg/kg. The study was conducted for 28 days with daily once dosing of extract. Animals were sacrificed on day 29 by decapitation. Blood was collected. Sera were separated and used for various biochemical assays. The testes, epididymis, vas deferens, seminal vesicle and prostate were dissected out. Sperm count, fructose content in seminal vesicles, histopathological studies and hormonal assay were conducted. Sperm count and fructose level in treated animal were increased significantly. The increased sperm counts and increased weight of sexual organs are indicative of improved fertility. Fructose is the mail source energy for sperm motility. The result concluded that the Methaolic fruit extract of Ficus auriculata possessed aphrodisiac activity.

Keywords: Ficus auriculata, Aphrodisiac activity, Wistar albino rats, Sperm count.

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