Abstract
FREE RADICAL SCAVENGING ACTIVITY OF NEW COUMARIN COMPOUNDS ISOLATED FROM CEROPEGIA JUNCEA (ROXB.)

Sudha Karayil*, Vivek. C. H., Sudheesh. P. S.

ABSTRACT

Plants are the source of natural products which act as models for new pharmacologically active compounds. Coumarin and its derivatives were all considered as phenylpropanoids. Many phenolic compounds were reported to be effective in therapeutic properties. Among them coumarin, is a compound found naturally in plants with broad biological functions. The plant Ceropegia juncea (Roxb.) is extracted and isolated for coumarins and were evaluated for their anti-oxidant activities (in vitro and in vivo). The results showed the percentage of scavenging activity of test coumarin on free radical generation. Coumarin scavenges DPPH radical in a dose dependent manner (1.0-300 μg/ml).

Keywords: Coumarin, Ceropegia, Antioxidant, Free radical scavenging.


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