Abstract
EVALUATION OF ANTIFUNGAL, ANTITUBERCULOSIS AND ANTIOXIDANT ACTIVITIES OF BLUMEA LACERA AND CYATHOCLINE PURPUREA (ASTERACEAE)

Sanjeevani D. Mane* and Vinod B. Shimpale

ABSTRACT

Two weed species i.e. Blumea lacera and Cyathocline purpurea were selected for evaluation of their antimicrobial activities. Plant extracts in their different concentrations were examined for antifungal activity, antioxidant activity and antituberculosis activity. Antifungal activity of both the species were studied with the help of MIC method against Aspergillus flavus, Alternaria alternata and Fusarium oxysporum. Antioxidant activity was performed by DPPH assay method using standard ascorbic acid and DPPH solution. While antimycobacterial activity of extracts were assesed against M.tuberculosis using MABA i.e. Microplate Alamar Blue Assay method. From all the three activities it was observed that weed extracts in different solvents are more sensitive for performed biological activities. At minimum concentration within the range of 200-300 ppm of concentration of extracts it inhibits fungal growth. Effect of radical scavenging activity in percentage also studied by using DPPH method. From antituberculosis activity different concentration of weed extract in μg/ml were studied for their sensitive and resistant nature. From these three activities it proves that both weed species shows better biological activities.

Keywords: Blumea lacera, Cyathocline purpurea, antifungal, antioxidant, antituberculosis.


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