Abstract
AN EFFICIENT APPROACH FOR THE SYNTHESIS OF 2-[(3-CYANO-1-OXO-4-(3, 4, 5- TRIMETHOXYPHENYL)-1, 2, 3, 4-TETRAHYDRONAPHTHALEN-2-YL) THIO] BENZOIC ACID DERIVATIVES

Chaitramallu, Dr. Devaraju Kesagodu* and Dr. Ranjini

ABSTRACT

A series of 2-[(3-cyano-1-oxo-4-(3, 4, 5-trimethoxyphenyl)-1, 2, 3, 4-tetrahydronaphthalen-2-yl) thio] benzoic acid have been synthesized with a significant stereo selectivity and improved yields in a single step by employing thiosalicylic acid in presence of Tetra-n-butylammonium bromide /methanol solvent system. The structures of the synthesized compounds were confirmed by spectral and elemental analysis data.

Keywords: thiosalicylic acid, tetra-n-butylammonium bromide, dehalogenation.


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