Abstract
PREVALENCE OF WEAK D AMONG BLOOD DONORS AT A TERTIARY CARE HOSPITAL IN TAMAKA, KOLAR, KARNATAKA

Dr. Subhashish Das*

ABSTRACT

Introduction: The study “Prevalence of Weak D among Blood Donors at a Tertiary Care Hospital in Tamaka, Kolar, Karnataka” was conducted in the Department of pathology Sri Devaraj Urs Medical College, over a period of 6 years from January 2012 to December 2017. Method: Blood samples that were negative for RhD by immediate spin tube method were tested for weak D by indirect antiglobulin test. Observation and results: Among 45272 healthy blood donors, 42853(94.65%) were RhD factor positive while, 2419(5.33%) were Rhd negative. Among these, 2419 RhD factor negative individuals 5 (0.20%) were weak D positive. Conclusion: Numerous studies conclude that weak D antigen is immunogenic and is capable of producing alloimmunisation if transfused to RhD negative subjects. Ergo, it is pertinent to also detect the Weak D or partial D status of those individuals who are negative with saline anti-D.

Keywords: Weak D antigen, Rh blood group.


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