Abstract
ROLE OF IMMATURE RETICULOCYTE FRACTION IN CLASSIFICATION OF HYPOREGENERATIVE ANEMIAS

Dr. Jayanti Nayak and Dr. Pramita Sahu*

ABSTRACT

Anaemia is a global health problem. India has a high prevalence of anaemia. Anemia is categorized to hypo-regenerative anaemias and regenerative anaemias based on the absolute reticulocyte count. The immature reticulocyte fraction (IRF) gives a basic idea about the marrow erythropoietic activity and its response to drugs and therapy at an early stage thereby useful for monitoring therapy by the physicians without seeing the marrow. In our study 312 cases of anemia were studied. The most common cause of hypo-regenerative anemia in our study was found to be megaloblastic anemia with 93 (29.8%) followed by iron deficiency anemia anemia (28.2%). There was no significant difference in Hb and reticulocyte percentages across the anemia groups, p>0.05, but the present study observed a weak but significant correlation while comparing IRF with RT%, ARC and Hb (p<0.05). The conclusion of the present study was, considering the ARC and IRF values along with peripheral smear examination give further clues to the differential diagnosis of anaemia and it can also aid in differentiation of aplastic anaemia from other causes of pancytopenia as true aplastic anaemia cases have zero IRF along with low reticulocyte count.

Keywords: Pancytopenia, Immature Reticulocyte Fraction, Aplastic anemia.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • OCTOBER ISSUE PUBLISHED

    OCTOBER 2018 Issue has been successfully launched on 1 October 2018

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 4.382 to 4.918 due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT