Abstract
THE INFLUENCE OF PROPYLENE GLYCOL AND PEG 400 AS PLASTICIZER AGAINST PHYSICAL PROPERTIES PATCH OF ARECA CATECHU L. SEEDS EXTRACT

Harista Dwiyani, *Rise Desnita and Sri Luliana

ABSTRACT

Extract of Areca catechu L. seeds was formulated in patch preparation. Components that affect the physical properties of the patch are polymers and plasticizers. The polymer that used was a combination of HPMC-PVA. While Propylene Glycol and Poly Ethylene Glycol (PEG) 400 as a plasticizer. The research aim is to determine the influence of Propylene Glycol and PEG 400 as a plasticizer on physical properties of the patch. The evaluation includes weight uniformity, the percentage of water content, thickness, tensile strength and the percentage of elongation patch. The results showed that Propylene Glycol plasticizer can produce the patch with average weight 0,4546 g, the percentage of water content 8,6731%, thickness 0,1898 mm, tensile strength 0,15 Kgf/mm2 and the percentage of elongation 65,2222%. While plasticizer PEG 400 produces patch with average weight 0,5032 g, the percentage of water content 7,4234%, thickness 0,2123 mm, tensile strength 0,5370 Kgf/mm2 and the percentage of elongation 58,95%. The conclusion is that Propylene Glycol and PEG 400 as plasticizers affect the physical properties of the patch including uniformity of weight, thickness, and tensile strength, which PEG 400 is the best plasticizer in patch formulation of A. catechu L extract.

Keywords: Patch, plasticizer, propylene glycol, PEG 400.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • OCTOBER ISSUE PUBLISHED

    OCTOBER 2018 Issue has been successfully launched on 1 October 2018

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 4.382 to 4.918 due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT