Abstract
CHEMOPROFILING OF HOMOEOPATHIC DRUG COFFEA CRUDA

Rakhi Mishra*, Manoj Kumar, Binit Dwivedi, B. S. Arya, Renu Arya, Anil Khurana and R. K. Manchanda

ABSTRACT

Chemoprofiling of homoeopathic drug/tincture (HT) represents a comprehensive approach for evaluation of quality, purity, safety and efficacy of HT. According to the phytoequivalence concept the full HT can be seen as the active compound, because the several constituents act together being responsible for its therapeutic effect. Coffea arabica (Coffee) is the healthiest beverages in the world is commonly called coffea cruda in homoeopathic system of medicine and frequently used in the treatment of insomnia, headaches, toothaches and labor pains. The main active constituents of Coffea cruda are caffeine, trigonelline, chlorogenic acid, quinic acid, tannic acid, tannin, fixed oil and proteins. Present study reveals the moisture content (3.683 %), Total Ash (2.66 %), Alcohol (6.48 %), Water extractive values (21.69 %), total solids (0.48 %), Wt/ml (0.82 g) and Alcohol content (90.0 %). In UV spectroscopy ╬╗max. at 280 nm shows presence of caffeine in HT. HPTLC analysis of in house HT, caffeine standard and three market sample were performed by using chloroform methanol (9:1, v/v) as mobile phase. Under UV light (254 nm), spot of caffeine was observed at Rf. 0.56 in above samples. However excess amount of caffeine content found in In-house HT rather than the market samples.

Keywords: Coffea arabica, Homoeopathic drug, Chemoprofiling, H.P.T.L.C fingerprint.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • OCTOBER ISSUE PUBLISHED

    OCTOBER 2018 Issue has been successfully launched on 1 October 2018

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 4.382 to 4.918 due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT