Abstract
SERUM TESTOSTERONE LEVEL IN TYPE 2 DIABETES MELLITUS MALES: A REVIEW IN URBAN POPULATION OF PAKISTAN.

Dr. Zulfiqar Khosa, *Dr. Mukhtar Mehboob and Dr. Muhammad Zubair

ABSTRACT

Background: High prevalence of low testosterone levels is evocative due to many chronic conditions, amongst which Diabetes Mellitus is at the top most. Creating such association decisively might contain concentrated results during execution of hypogonadism and diabetes mellitus. In Pakistani atmosphere these outcomes have to be established in association to diabetic individuals, therefore an expressive study has been done to validate these results. Objective: This study was carried out to assess total testosterone concentration in male type 2 diabetes patients with their age and BMI corresponding controls and observe the correlation among type 2 diabetes mellitus and serum testosterone levels. Methods: This cross sectional study which was carried out in Baqai Institute of Diabetology and Endocrinology Karachi, and Mohtarma Shaheed Benazir Bhutto Hospital Quetta on 200 male patients of type 2 diabetes mellitus with BMI and 50 matched male controls were studied with their serum testosterone concentrations measured. Results: The mean age of controls was 35.9 years and that of diabetic cases was 42.7 years. The mean BMI of controls was 23.2 Kg/m2 while in diabetic cases it was 28.6 Kg/m.2The testosterone levels among diabetic cases was 2.47 ng/dl which was much lower than the testosterone level seen in control mean 6.23 ng/dl done in age and BMI groups. 139 (69%) diabetic cases had low testosterone level while 61 (31%) cases had normal level of testosterone. This ratio among control was 03 (6%) low testosterone level while 47 (94%) had normal testosterone levels seen. Conclusions: Serum testosterone levels are considerably lower in type 2 diabetes mellitus individuals irrespective of BMI and age.

Keywords: Testosterone and Diabetes mellitus.


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