Abstract
AMELIORATIVE EFFECT OF PLANT EXTRACTS OF SURUHAN (PEPEROMIA PELLUCIDA) ON BLOOD GLUCOSE AND LIBIDO OF MALE MICE INJECTED WITH ALLOXAN

Mohammad Kanedi*, Sutyarso, Hendri Busman, Cahyani Intan Kesuma, Yulianty and Martha Lulus Lande

ABSTRACT

This study was conducted to determine the effect of plant extracts of suruhan (Peperomia pellucida L. Kunth) on the blood glucose level and libido of alloxan-induced male mice. By using a completely randomized design, 25 male albino mice were grouped into five with five replications each. Group 1 treated with alloxan at the dose of 150 mg/kg bw (as negative control). Group 2 was given alloxan and glibenclamide of 0.65 mg/kg bw (as positive control). Group 3, 4 and 5 were treated with alloxan and plant extracts at the dose of 56, 112 and 168 mg/kg bw respectively. Injection of alloxan was done 3 times in 6 days and the plant extract was given every day for 35 days. Results showed plant extracts of suruhan significantly lowering blood glucose levels, shortening courtship and mounting latency, as well as increasing mounting frequency of the mice. It suggests that plant extract of suruhan is potent to be used as anti-hyperglycemic and libido enhancing agents in male subjects.

Keywords: suruhan, Peperomia pellucida, hyperglycaemia, diabetes, male libido.


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