Abstract
REVIEW ON PROTEOMICS: APPROACH TO DRUG DEVELOPMENT

Poornima Soni, Kamlesh Choure and Himesh Soni*

ABSTRACT

Drug discovery is a long-lasting and highly expensive process that uses a variety of tools from diverse fields. Proteomics, is defined as the total protein content of a cell or that of an organism. Proteomics helps in considerate of modification in protein expression during different stages of life cycle or under stress condition. Proteomics helps in illustrating the structure and function of different proteins as well as protein-protein interactions of an organism. Proteomics has wide applications on drug development against several diseases. Variation in protein expression profile of normal and diseased person may be analyzed for target protein. Protein to gene may be predicted. Once protein/gene is identified, function may be predicted. This can assist in disease management which leads to the drug development. The present review aims to provide a basic considerate of proteomics research in field of drug development.

Keywords: Proteomics, Protein structure, Metabolomics & Drug development.


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