Dr. Sruthi Prasad* and Dr. Pallavi Saxena


Introduction: Diabetes mellitus(DM) is a global pandemic with high mortality and morbidity due to its long term microvascular and macrovascular complications. Altered platelet morphology and function play a key role in the pathogenesis of DM and its vascular complications. This is reflected as a change in various platelet indices such as Mean Platelet Volume, Platelet Distribution Width and Platelet Large Cell Ratio. The aim of study is to evaluate platelet distribution width(PDW) in diabetic patients and compare it with a non diabetic control group. We also attempted to compare PDW within the diabetic cohort amongst those with and without microvascular complications. Methodology: The study was carried out on patients with DM, attending the medicine out-patient department. Relevant history, fasting blood glucose and hematological parameters (platelet indices and complete blood counts) were assessed as part of the routine investigations. A total of 320 diabetics were screened for the study. After applying exclusion criteria, 52 diabetics and also 62 non-diabetic controls were included in the study. Statistical analysis was done. Results: The PDW was significantly higher in diabetic patients when compared to the control group, (p=0.000022). Among the diabetics, PDW was significantly higher in those with microvascular complications as compared to those without (p=0.00223). Conclusion: Evaluation of PDW provides an insight into the pathogenesis of DM and also its microvascular complications. PDW is a simple, cost effective haematological investigation, which can possibly be used as a screening tool in DM patients and a prognosticator of diabetic microvascular complications.

Keywords: Platelet Distribution Width, Diabetes Mellitus, Microvascular complications.

[Full Text Article]


Forgot Password  |  Register


Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation


    APRIL 2019 Issue has been successfully launched on 1 April 2019

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 4.382 to 4.918 due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.


  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.


UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS


Copyright From

Covering Letter

                        Author Instruction