Abstract
STUDY THE EFFECT OF SOLVENT ON MOLAR REFRACTION AND POLARIZABILITY CONSTANT OF CLARITHROMYCIN SOLUTION AT 303.15 K.

J. P. Nehete* and A. N. Sonar

ABSTRACT

The molar refraction and molar polarizability constant of substituted heterocyclic drugs Clarithromycin in different solvent like Ethanol, Methanol, Carbon tetrachloride, DMF, Dioxane and THF medium at 303.15 K at different concentrations were studied. The values of molar refraction (Rm) and molar polarizability (α) constant are found to be decreased with decreasing concentration of solute in solvent and drug –solvent interaction in different solvent has been observed.

Keywords: Refractive index, Molar refraction and Molar polarizability constant.


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