Abstract
SEMINIFEROUS HYPERTROPHY IN MALE WISTAR RAT ADMINISTERED WITH GORDON DRY GIN (MORINGA CITRUS BLEND)

Eric Emmanuel Uchenna* and Harrison Oju Uket

ABSTRACT

The consumption of herbal products has in recent times increased worldwide especially among the people of Africa. Gordon dry gin moringa citrus blend is an alcoholic drink composed of mainly moringa, alcohol and citrus. This study seeks to ascertain the histological effect of Gordon dry gin on the liver and testes of adult rats. Thirty five (35) adult male rats weighing 120±20g-180±30g were used for the study and were allowed to climatize for two weeksand administered with the various treatment for three weeks. They are divided into five groups designated group A,B,C,D. Group A(control)received water and feed. Group B; group B1 and B2 received high and low doses of Gordon dry gin (moringa citrus blend) respectively. Group C; C1 and C2 received high and low doses of 43% of alcohol respectively. Group D; D1 and D2 received high and low doses of 200mg/kg of moringa leaf extract respectively. At the end of 21 days the animals were sacrificed, the liver and the testes harvested, fixed in 10% formal saline and the tissue processed in parrafin wax. The photomicrograph of the liver showed no significant change at the dose administered in all the groups. The photomicrograph of the testes showed enlargement in the size of the seminiferous tubule measuring 2.6cm in group B and 2.8cm in group C.Conclusion the dose of moringa citrus blend used in this work did not produce any significant effect on the liver but hypertrophic effect was seen in the testes.

Keywords: Gordon dry gin, testes, liver, moringa, seminiferous tubules.


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