Abstract
CLINICAL AND METABOLIC EFFECTS OF INTRA ARTICULAR STEROIDS IN RHEUMATOID ARTHRITIS

Vidya S. and Dr. P. S. Sairam*

ABSTRACT

Introduction: Local steroids have always been considered a safer alternative to systemic steroids. But there are only few Indian studies regarding the metabolic effects of Intra articular steroids (IAS) in patients with rheumatoid arthritis (RA). Aim & Objectives: To assess the metabolic effects of intra articular steroids in rheumatoid arthritis patients who had low disease activity but for persistent pain over few joints. Methodology: Intra-articular steroids were given to patients with rheumatoid arthritis with low disease activity and a few inflamed joints. Metabolic parameters, disease activity scores (DAS 28, CDAI) and pain score (VAS) were assessed before and after injections (at 2 days and 4 weeks). Results: There were significant increases in neutrophil count (p<0.001), serum total proteins and globulins (p<0.05), decreases in lymphocyte count (p<0.001), VAS score for pain (p<0.001), systolic and diastolic blood pressure (p<0.05) at 2 days. There were significant decreases in CDAI, DAS 28 & VAS scores (p<0.001) & ESR(p<0.05) at 4 weeks. Conclusion: There were transient changes in metabolic parameters at 2 days which were not evident at 4 weeks. There was a significant decrease in disease activity and pain at 4 weeks.

Keywords: Intra articular steroids (IAS), rheumatoid arthritis (RA).


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • NEW MARCH ISSUE PUBLISHED

    MARCH 2019 Issue has been successfully launched on 1 March 2019

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 4.382 to 4.918 due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT