Abstract
STUDY OF SENSORINEURAL HEARING LOSS IN PATIENTS OF HEAD AND NECK CANCERS AFTER RADIO-CHEMOTHERAPY

Dr. V. P. Singh, Dr. Nikunj Jain* and Dr. Richa Gupta

ABSTRACT

 Introduction: The multimodality approach in locally advanced squamous cell carcinoma of head and neck has been found to reduce the risk of local failure and improves survival. Radiation treatment strategies have not been adopted to protect the inner ear. Radiation damage can thus occur from the pharyngo-tympanic tube to the brain stem auditory pathway and therefore may cause hearing loss.  Materials and methods: A total of 100 Histopathologically proved Head and Neck cancer patients were selected, out of which 66 patients were subjected to radiotherapy and 34 patients were subjected to concomitant chemoradiation to study the occurrence of SNHL from oct2017 to jan2019.  Results: The sensorineural hearing loss was more in higher frequencies. A paired sample t-test was conducted to compare the hearing losses before and 6, 12 months after therapy and were found to be significant (p<0.05). It was found that hearing loss was persistent. The difference of proportions of hearing loss after RT and RT+CT (p<0.05) after 1 month were found to be significant.  Conclusion: As the radiation field descends down from nasopharynx effect on otological structures decreases. Both incidence and severity of hearing loss increased with time especially at high frequencies. Patients who received concomitant chemoradiation experienced greater sensorineural hearing loss compared with patients treated with radiotherapy alone.

Keywords: Sensorineural hearing loss, radiotherapy, chemotherapy, head and neck.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • NEW MARCH ISSUE PUBLISHED

    MARCH 2019 Issue has been successfully launched on 1 March 2019

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 4.382 to 4.918 due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT