Abstract
FORMULATION AND EVALUATION OF TABLET DOSES FORM ALONG WITH ANTIMICROBIAL DRUG

Anil Kumar Gangwar* and Md. Semimul Akhtar

ABSTRACT

Antiinfective chemotherapy is the science of administering chemical agents to treat infectious diseases. The fluoroquinolone market is heavily dominated by norfloxacin, ofloxacin, ciprofloxacin, etc. The 6-fluoroquinolones (also known as 4-quinolones or quinolones are a series of synthetic antibacterial agents derived from, or related to, nalidixic acid and oxolinic acid. Pharmacology Fluoroquinolones inhibit the replication and transcription of bacterial DNA, which eventually culminate in cell death. A tension is created in this remaining double helix which must be relived in order to continue the process. This enzyme has an important role in partitioning of chromosomal DNA during bacterial cell division and may be the primary target of fluoroquinolone activity in Gram positive bacteria cell.

Keywords: Antimicrobial Drug, Solid doses form, evaluation, formulation, FTIR.


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