Abstract
MOLECULAR DETECTION OF CHLAMYDIA TRACHOMATIS INFECTION IN INFERTILE AND PREGNANT WOMEN ATTENDING ASSISSTED CONCEPTION CLINICS IN PORT HARCOURT, NIGERIA

Faustina Ugochinyelum Amu* Gloria Ngozika Wokem and Easter Godwin Nwokah

ABSTRACT

Chlamydia trachomatis (CT) infections remain a leading sexually transmitted disease throughout the world and studies have linked this infection to adverse pregnancy, female infertility and poor outcomes in infant health. This study was to evaluate the prevalence of this infection among infertile women attending assisted conception clinics (Case study group) and those attending antenatal clinics (Control group) in Port Harcourt, Nigeria. A total of 120 endocervical swab samples were obtained from consenting women, sixty (60) from each group. A polymerase chain reaction (PCR) based method was used for the detection of this infection. Overall prevalence rate was 60% (72 0f 120). The result further revealed a statistically non-significant (p=0.480) higher rate among the infertile women (39(65%) of 60) as against 33(55%) of the 60 pregnant women (control group). The greater percentage of the positive cases was within the 25-34 age group in both subjects and this age group is known to be more sexually active. Results also showed that 15.8% of the total subjects were asymptomatic. In conclusion, this study has revealed that the infection is significantly present in the two groups and could be a major contributor to increase in adverse pregnancy outcomes and infertility as seen presently. 15.8% asymptomatic rate is of great concern and all these therefore underscore the urgent need for more awareness in our local setting, regarding this infection, especially on early diagnosis to guide management and care.

Keywords: Chlamydia trachomatis, Polymerase Chain Reaction, Infertile women, Pregnant women.


[Full Text Article]

Login





Forgot Password  |  Register

Indexing

Best Paper Awards

European Journal of Biomedical and Pharmaceutical Sciences (EJBPS) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.

Best Article of current issue :

Tangudu Nagabhusana Rao

Download Article : Click here

News & Updation

  • NEW APRIL ISSUE PUBLISHED

    APRIL 2019 Issue has been successfully launched on 1 April 2019

  • EJBPS New Impact Factor

    Its our Pleasure to Inform you that EJBPS Impact Factor has been increased from 4.382 to 4.918 due to high quality Publication at International Level.

  • Index Copernicus Value

    EJBPS Received Index Copernicus Value 77.3, due to High Quality Publication in EJBPS at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in EJBPS coming Issue.

     

UG/PG/Ph.D Research Publication

Research Scholar of UG/PG/Ph.D can Submit their Research Article/Review Article/Case Study/Short Communication for Publication in EJBPS

Downloads

Copyright From

Covering Letter

                        Author Instruction 
 

PLAGERLUM REPORT